Predominantly affecting young adults and adults, cases of dengue fever spread slowly on Maui, Oahu, and Kauai. Dengue viruses are transmitted by the bite of an infected female Aedes subgenus Stegomyia mosquito. The first epidemic of dengue hemorrhagic fever in the modern era was described in Manila in It is caused by infection with 1 of the 4 serotypes of dengue virus, which is a Flavivirus a genus of single-stranded nonsegmented RNA viruses.
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Natural history of plasma leakage in dengue hemorrhagic fever: Classic dengue fever is marked by rapid onset of high fever, headache, retro-orbital pain, diffuse body pain both muscle and boneweakness, vomiting, sore throat, altered taste sensation, and a centrifugal maculopapular rash, among other manifestations. In Indonesia, young adults in Demak and provincial areas make up a larger percentage of infected patients.
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Practice Essentials Dengue is the most common and important arthropod-borne viral arboviral illness in humans. New strategy against Aedes aegypti in Vietnam. A 5-year prospective study in Thai children examined the herdarah economic burden of dengue infection in children on the local population.
Mosquitoes acquire the virus when they feed on a carrier of the virus. A prospective study examined the direct and indirect costs of dengue infection in pediatric and adult patients in 8 countries.
Evaluation of the NS1 rapid test and the WHO dengue classification schemes for use as bedside diagnosis of acute dengue fever in adults.
A aegypti breeds year-round in southern Florida. This child's capillary refill at 6 seconds was delayed well patofisioloti a normal duration of 2 seconds. Cuban studies have shown that stored serum sample analysis demonstrated progressive loss of cross-reactive neutralizing antibodies to DENV-2 as the interval since DENV-1 infection increased.
Pathophysiology Dengue fever is a mosquito-borne viral disease caused by 1 of 4 closely related but antigenically distinct serotypes of dengue virus, serotypes DENV-1 through DEN Less frequently, isolation of the dengue virus from serum, plasma, leukocytes, or autopsy samples.
Dengue continues to extend its range. Over patofissiologi past decades, the GeoSentinel Network of Travel Medicine providers has demonstrated that dengue has become more frequently diagnosed than malaria in travelers returning from tropical areas other than Africa.
After an incubation period of days, the infected mosquito can transmit virus for the rest of its life span 2 weeks to 1 month.
Dengue infection in pregnancy. Transaminase levels paotfisiologi be mildly elevated or present in the several thousands associated with hepatomegaly in those patients with acute hepatitis.
Pediatr Infect Dis J. Indian J Med Microbiol. Neutralizing antibodies after infection with dengue 1 virus. Admission to an intensive care unit is indicated for patients with severe dengue see Treatment. The overall incidence of dengue, as well as the explosive outbreaks of dengue, has been increasing dramatically over the last several years. The distribution of dengue is geographically determined.
High levels of interferon alpha in the sera of children with dengue virus infection. In the Americas, dengue epidemics were rare post war because Aedes mosquitoes ppatofisiologi been eradicated from most of the region through coordinated vector-control efforts.
Globally, Aedes aegypti is the predominant highly efficient mosquito vector for dengue infection, but the Asian tiger mosquito, Aedes albopictusand other Aedes species can also transmit dengue with varying degrees of efficiency see the images below. In the last 50 years, patofisiologk incidence of dengue has increased fold worldwide.
Share cases and questions with Dengud on Medscape consult. Certain nonhuman primates in Africa and Asia also serve as hosts but do not develop dengue hemorrhagic fever. Hyperendemic circulation of all 4 dengue serotypes is present in the northern countries of South America.
Clinical features and pitfalls in the laboratory diagnosis of dengue in travellers. The virus is in the family Flaviviridae, genus Flavivirus, and the type-specific virus is yellow fever. The dengue virus has 4 related but antigenically distinct serotypes: Classic dengue fever primarily occurs in nonimmune, nonindigenous adults and children and is typically self-limiting.
The mean cost of illness from dengue was significantly higher than that from other febrile illnesses studied.